Sounds like a wiring issue. I would start at the head unit and work my way through everything. Check HU to AMP connections, RCA cables and remote power lead. Make sure all connections are solid, nothing loose. Then check AMP to power and ground, same thing, make sure everything is solid. If all good there start playing with the tower wires, but would hope you find the issue before getting to this point.

Are you using a distribution block for both power and ground?

Good luck, electrical is a beast. Good looking setup though!