David,
I prefer the charger on the front wall because you never have to mess with it, and if you do, it's four screws and a couple of quick disconnects, but nothing to adjust.
Then I prefer the amplifiers lined up against the port hull. Easier to tune or access for diagnostics and service.
Quality heavy gauge cable is very expensive for that amount of current without loss and for that distance. Also, you wouldn't want to double the length of the starter/alternator feed without stepping up the gauge. So in any scenario applied to this boat, I just don't feel good about splitting up the batteries.

David